Other associated endocrine features that support the diagnosis are as follows: early‐onset hypothyroidism due to TSH resistance, which is the most common associated endocrine alteration, being present in nearly 100% of PHP‐1a patients; hypogonadism (due to FSH and LH resistance); and GH deficiency (due to GHRH resistance).10 Here, PLOD1 is linked to hypogonadism.