PRL and Menstrual disorder: •Menstrual disorders •Anovulation •Galactorrhea •Breast enlargement •prolactin-sensitive dysplasia •Gynecomastia •decreased fertility •decreased estrogen and testosterone production •Impotence in men •Decreased libido •retrograde or painful ejaculation •erectile dysfunction •orgasmic dysfunction   •Syndrome: Amenorrhea - Galactorrhea Azoospermia - Gynecomastia