GDF15 and cardiac hypertrophy: The development targets for detection and treatment of myocardial hypertrophy mainly focus on micro-RNAs, vascular endothelial growth factor, NAD-dependent deacetylase sirtuin-3 (SIRT3), growth/differentiation factor 15 (GDF15), transmembrane protein glycoprotein 130 (Gp130), CaMKII, Chloride channel-3 (ClC-3), and adhesion molecules [14].