All five asthma-associated CNVs showed consistent effect sizes in a sensitivity analysis that excluded cases and controls with common allergic conditions: HLA-DQA1/HLA-DQB1 (0.87 [0.84–0.89], p = 1.20 × 10–24), PRKRA (1.13 [1.10–1.16], p = 4.25 × 10–17), MUC22 (1.04 [1.00–1.08], p = 0.048), TAP2 (1.09 [1.06–1.12], p = 3.12 × 10–8), and FBRSL1 (1.08 [1.04–1.12], p = 0.0001). The gene discussed is HLA-DQB1; the disease is asthma.