Bonferroni post-test analysis revealed that the level of spermatogenic cell marker was significantly reduced in the CRS + NS group compared with Control + NS group (AR:t = 4.961, P = 0.0008; CD29:t = 4.070, P = 0.0040; INSL3:t = 4.289, P = 0.0019), which was reversed by BET treatment (AR:t = 3.355, P = 0.0155; CD29:t = 1.999, P = 0.2009; INSL3:t = 12.59, P < 0.0001). The gene discussed is ITGB1; the disease is congenital rubella syndrome.