CD8A and intrahepatic cholangiocarcinoma: As expected, the patients with ICC harbouring high CD8+ TIL and low FoxP3+ TIL counts in the intra-tumour exhibited the most favourable OS whereas those with low CD8+ TIL and high FoxP3+ TIL counts in the intra-tumour exhibited the worst OS (P < 0.001, log-rank test; Fig. 3c).