SACK1B and thyroid cancer, nonmedullary, 2: Considering FTC and PTC tissues and their unpaired metastases (FTC- and PTC-derived MTS), we observed that FAM83B mRNA level were significantly lower in FTC-derived MTS compared to primary FTCs (p < 0.05), whereas the decrease observed between PTCs and PTC-derived MTS was not significant (Fig. 2E,F).