LRRK2 and Parkinson disease: We observed that EAAT2 protein was nearly absent in the caudate and putamen of LRRK2 G2019S PD patients as compared to healthy controls (Fig. 1a, b; LRRK2 G2019S PD patient cases vs age-matched controls; p = 0.01), and this difference affected both the multimeric and monomeric fractions (Supplementary Fig. 1a–c, online resource; LRRK2 G2019S PD patients vs age-matched controls: a, p = 0.004; b, p = 0.006; c, p = 0.012).