In the endotoxemia model, pretreatment with Cel followed by LPS significantly reduced serum levels of ALT, AST and urea ((P < 0.01 or P < 0.05, Fig. 1b), while it increased the UA level, but the difference was not statistically significant (P > 0.05, Fig. 1b). Here, GPT is linked to serum lipopolysaccharide activity.