A number of pTyr proteins were captured by the Src superbinder photo-pTyr-scaffold efficiently in wild-type BT549 cells but much less efficiently in Kindlin-2 knockdown BT549 cells (Fig. 1A and Supplementary Table S1), suggesting a direct or indirect role of Kindlin-2 in regulation of EGF-induced tyrosine phosphorylation of these proteins in breast cancer cells. This evidence concerns the gene EGF and breast carcinoma.