Because we recently found that STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia (CLL) and multiple myeloma cells [15], and because the JAK-STAT pathway is constitutively activated in MF [13, 14], we wondered whether STAT3upregulates GLI1 in MF fibrocytes. The gene discussed is GLI1; the disease is B-cell chronic lymphocytic leukemia.