TGFB1 and colorectal carcinoma: To confirm that the effects seen were EV‐dependent, fibroblasts were conditioned with fluorescently labelled (DiO) CRC EVs (epithelial or mesenchymal), stimulated with TGF‐β and sorted into EVhigh (70–100th centile fluorescence intensity) and EVlow (0–30th centile) populations, to distinguish fibroblasts with high and low concentrations of internalised EVs (Figure S5A).