Bulgarian population had a higher number of deleterious variants in ATM and MUTYH; Ashkenazi Jewish population contained the three well-known BRCA founder mutations [BRCA1 185delAG(c.68_69del), 5382insC(c.5266dup), and BRCA2 6174delT(c.5946del)] (Abeliovich et al, 1997); of the only six deleterious variants in Estonian population, two were in ATM; BRCA2 c.771_775del (999del5), a founder mutation in Icelander for breast cancer (Tulinius et al, 2002), was not but BRCA2 c.8904del was present in the Icelander population. This evidence concerns the gene MUTYH and breast carcinoma.