For example, Fanconi Anemia caused by 12 mutated DDR genes of FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, RAD51C, SLX4, XRCC2, and ERCC4 are all autosomal recessive, whereas breast cancer caused by eight DDR genes of BARD1, BRCA1, BRCA2, BRIP1, CHEK2, PALB2, RAD51D, and RAD54L are all autosomal dominant. This evidence concerns the gene CHEK2 and Fanconi anemia.