While phosphorylation of either AMPKα1 and AMPKα2 activates AMPK and the phosphorylation of both AMPKα1 and AMPKα2 at Thr172 is regulated by eIF3a, AMPKα2 is much less abundant than AMPKα1 in the NSCLC cells tested in this study. Here, EIF3A is linked to non-small cell lung carcinoma.