In the analysis of DEGs induced by viral infection, upregulated genes, such as GNPDA1, were found to be highly expressed in the kidney, as well as RPAGD, ANKH and PRODH in the thyroid, pancreas, and small intestine, respectively, and downregulated genes were highly expressed in the bone marrow, lymph nodes, spleen, lung, caecum, gallbladder, and bladder. The gene discussed is GNPDA1; the disease is viral infectious disease.