Persistent inflammation and dysregulated host response of lung repairIncreased plasma biomarkers of lung inflammation and fibrosis (Lipocalin 2, Matrix metalloproteinase-7, Hepatocyte growth factor)Persisting inflammation in lungs, mediastinal lymph nodes, spleen, and liverInvolvement of iron homeostasis disturbances in end-organ damageRelationship between metabolic abnormalities and lung sequelae. This evidence concerns the gene LCN2 and inflammatory response.