Particularly, HIS-SARS2 could upregulate inflammation-associated genes in transformed human embryonic kidney cell HEK293T, human fetal lung fibroblast cell MRC5, and human umbilical vein endothelial cell (HUVEC), which is consistent with the finding that the infection of SARS-CoV-2 could lead to multiple organ damage (such as lung, kidney, and liver) by stimulating an inflammation response [273–276]. The gene discussed is SARS2; the disease is infection.