g.,ERCC2/XPD,ERCC3/XPB,ERCC4/XPF,ERCC5/XPG,ERCC6/CSB, andERCC8) in the NER pathway frequently cause Xeroderma pigmentosum, trichothiodystrophy, or Cockayne syndrome[116]. This evidence concerns the gene ERCC4 and xeroderma pigmentosum.