PTH and chronic kidney disease: Recently, our group analyzed a cohort of 28‐week‐old CKD rats and found that despite having low kidney function and high PTH versus control rats, microcomputed tomography detected no structural and limited mechanical changes in the long bones.(22) Therefore, we hypothesized that performing Raman spectroscopy and nanoindentation on 28‐week‐old specimens may reveal changes in the bone matrix that precede pore formation.