As a result, NURR1 is essential to the generation and functioning of the dopaminergic circuitry (Kadkhodaei et al., 2009; Saucedo‐Cardenas et al., 1998; Smidt & Burbach, 2007; Solomin et al., 1999; Zetterström et al., 1997) and its deregulation is involved in the development of DA‐associated brain disorders, such as PD (Jankovic et al., 2005; Montarolo et al., 2016). The gene discussed is NR4A2; the disease is brain disorder.