As shown by the enrichment analysis results, TNF, IL-10, TGF-β1, EGF, CXCL16, CCL21, SERPINB5, SERPINA1, SOD2, and PPIG were the important targets, and TNF, IL-10, TGF-β1, and EGF were the major core targets for compound Danshen tablets in reversing hepatic fibrosis. This evidence concerns the gene CCL21 and Hepatic fibrosis.