Subsequent results illustrated that the depletion of E2F1 led to reduced transplanted tumor volume (p < 0.001) and weight (p < 0.01) in vivo, in addition to diminished LINC00152 and E2F1 expression levels (all p < 0.001), and decreased Ki67 positive expression (p < 0.01) (Figures 5(a)–5(f)). The gene discussed is MKI67; the disease is neoplasm.