SETBP1 and cancer: In order to find more significance related to the FAMILIAL cancer, we only retained the exonic area and presented as “nonsynonymous” or “frameshift.” After filtering, three genetic variants appeared in individuals with Basan syndrome but not in non-Basan individuals: rs3085861 (SETBP1), rs663651 (SETBP1), and rs2454206 (TET2).