ATXN2 and spinocerebellar ataxia 7: The promoter regions of ATXN2 and ATXN3 are methylated in SCA2 and SCA3 patients with expanded repeats (Laffita-Mesa et al., 2012; Wang et al., 2017), and increased levels of methylation are found in the CTCF binding domains of ATXN7 in SCA7 patients (Libby et al., 2008).