KMT2B (lysine methyltransferase 2B), also known as MLL2 (mixed lineage leukemia 2), belongs to the family of mammalian histone H3 lysine 4 methyltransferases and is known to be involved in the development of several cancers (Li et al., 2020; Klonou et al., 2021). This evidence concerns the gene KMT2B and cancer.