Furthermore, GSDMB expression in primary tumors is only partially correlated to its expression in healthy tissue; further profiling of tissue samples from 75 gastric and 80 esophageal cancers revealed that only 45% of gastric tumor samples and 55% were positive for GSDMB, despite virtually all of the corresponding healthy tissue sections showing robust GSDMB expression (79). The gene discussed is GSDMB; the disease is esophageal cancer.