A phase I/II clinical trial involving BNZ-1-targeted T-cell malignancies CTCL and LGLL has been completed (NCT03239392), and the efficacy of BNZ-1 and BNZ-2 (IL-15/21) is currently being evaluated in alopecia areata and refractory coeliac disease, respectively (46). The gene discussed is IL15; the disease is alopecia areata.