When adjusted for likely confounders, including age, gender, hypertension, total protein, albumin, lymphocyte, lactic dehydrogenase, and lymphocyte, similar association between PC ratio and initial GI involvement remained for 2nd tertile (OR = 0.94 [95% CI: 0.24, 3.59]; p=0.923) and 3rd tertile (OR = 0.18 [95% CI: 0.03, 0.97]; p=0.005) when compared to the 1st tertile. The gene discussed is ALB; the disease is Hypertension.