Nearly half of the LD block of allergy variants (55 out of 93 SNPs) overlapped with the regulated actQTL peak and one of the variants, chr17:42,266,938 (rs34129849), also mapped to a 629-bp open chromatin region (chr17:42,266,595–42,267,224) located in intron one of the STAT5B gene (Figure 4D; Table S3). This evidence concerns the gene STAT5B and allergic disease.