BRCA1 and cancer: Experiments verified that the miR-205-5p/BRCA1/RAD17 axis increased the level of γ-H2AX and made DNA repair inefficient in head and neck squamous cell carcinomas in vivo and in vitro (Foray et al., 2003; Valenti et al., 2019), revealed that miR-205-5p/BRCA1/RAD17 axis had the potential to be a therapeutic target for cancer.