The independent risk factors for in‐hospital death included age >65 years old, complication of diabetes, renal impairment on admission (Cr > 73 μmol/L and eGFR < 60 ml/min 1.73 m2), WBC > 9.5 × 109/L and ALB < 35 g/L. The gene discussed is ALB; the disease is diabetes mellitus.