KCNQ1 and major depressive disorder: A SNP association in KCNQ1 with alcohol dependence was previously reported from a GWAS of European Americans [38], and the CACNA1S gene region, along with other calcium channel genes, was associated with major psychiatric disorders from a GWAS meta-analysis of schizophrenia, bipolar disorder, major depressive disorder, autism, and attention-deficit/hyperactivity disorder [28].