All tested NEC and other grade 3 NEN expressed ATRX (n = 12 NEC, n = 10 other NEN) and were negative for high-risk papillomavirus by in situ hybridization (n = 11 NEC, n = 9 other NEN) (Supplementary Table S8). The gene discussed is ATRX; the disease is neuroendocrine carcinoma.