NEC as a group and SCNEC were each more likely than grade 3 NET to be ER negative (69% NEC and 71% SCNEC vs 0% grade 3 NET; p = 0.005 and p = 0.007, respectively) and GATA3 negative (67% NEC and 67% SCNEC vs 0% grade 3 NET, p = 0.013 and p = 0.021, respectively) (Supplementary Tables S3 and S8). This evidence concerns the gene GATA3 and neuroendocrine carcinoma.