Pathogenic missense [3] and truncating mutations [4] of TINF2 are causative for dyskeratosis congenita (DC), a rare, dominantly inherited bone marrow failure syndrome characterized by mucocutaneous abnormalities and cancer predisposition, most commonly head and neck cancers, anorectal squamous cell carcinoma, and stomach and lung cancer [5]. This evidence concerns the gene TINF2 and dyskeratosis congenita.