Pathogenic missense [3] and truncating mutations [4] of TINF2 are causative for dyskeratosis congenita (DC), a rare, dominantly inherited bone marrow failure syndrome characterized by mucocutaneous abnormalities and cancer predisposition, most commonly head and neck cancers, anorectal squamous cell carcinoma, and stomach and lung cancer [5]. Here, TINF2 is linked to bone marrow failure syndrome.