Three of these genes, JAK1, FUBP1, and RBM15, are all associated with liver, blood, colorectal and pancreatic cancers; three, TPR, CDC73 and PIK3C2B are all associated with blood and colorectal cancers; and five, JUN, NEGR1, VTCN1, DDR2 and PBX1, are associated with blood, liver, pancreatic, sarcoma and gastric cancer, respectively. The gene discussed is PIK3C2B; the disease is familial pancreatic carcinoma.