A published dataset investigating transcriptomic differences between five skeletal muscle and 101 rhabdomyosarcoma patient samples (GSE108022) found that VANGL2/RHOA, components of WNT signalling, were important in the regulation of growth and self-renewal of embryonal rhabdomyosarcoma (ERMS) cells27. Here, RHOA is linked to embryonal rhabdomyosarcoma.