Immunohistochemistry analysis for various cell surface receptors such as DR4, DR5, and EGFR showed diverse levels in the tumor blocks from three patient tissue samples (Fig. 1e) and corresponding GBM models derived from the patient-derived cell lines, GBM8, GBM18, and GBM31R (Fig. 1f). This evidence concerns the gene TNFRSF10B and glioblastoma.