cDCs, homing by CCR6/CCL20 axis, involved in immunomodulation and were found increased in the synovial fluid in RA, idiopathic inflammatory myopathies dermatomyositis, and polymyositis.37 Taken together, these immune cells may underlie the key immunomodulation in the IC development and progress. The gene discussed is CCL20; the disease is rheumatoid arthritis.