Clinically, HCC patients with high ZEB1 expression had obviously shorter overall survival, comparing with low ZEB1 expression (p = 0.0134) (Fig. 7F), and high ZEB1 expression in HCC patients was related with pathological grading (p = 0.0022), and TNM stage (p = 0.0052) (Table S2). Here, ZEB1 is linked to hepatocellular carcinoma.