TNF and neoplasm: Meanwhile, the ratios of CD8+IFN-γ+ T (Fig. 7l), CD8+ IL-2+ T (Fig. 7m), CD8+TNF-α+ T (Fig. 7n), and CD8+Granzyme B+ T (Fig. 7o) cells in the splenocytes of Cal/ICG@MPs with 808 nm laser irradiation-treated mice was significantly increased after tumor antigen restimulation.