In addition, the protein expression levels of Beclin-1, LC3, and Bax in the MI group were higher than those in the sham group, while the levels of Bcl-2 protein were lower in the MI group than in the sham group (Fig. 2F, G), indicating an increase in myocardial autophagy and apoptosis in MI mice. Here, BECN1 is linked to myocardial infarction.