IPO7 and pachyonychia congenita: Additionally, IPO7 was revealed to be remarkably higher in PC cell lines (PANC-1, HPAC, BxPC-3, and Capan-2) than in immortalized normal pancreatic ductal epithelial cell line (hTERT-HPNE) by qRT-PCR and Western blotting (Fig. 1F‒G).