Interestingly, a punctual analysis comparing homozygous subjects for the haplotype group NAT2*5 (n = 29) with all other compound heterozygous SA subjects carrying a NAT2*5 haplotype (n = 37) revealed an increased risk of the former to develop anti-TB DIH (Fig. 2), even in an unbiased logistic model (OR 4.97, 95% CI 11.47-16.8, p = 0.01; Table V). Here, NAT2 is linked to tuberculosis.