The patient’s characteristics including age, Body mass index (BMI), Erythrocyte Sedimentation Rate (ESR), C-reactive protein (CRP), RA Factor, anti-citrullinated protein antibodies (ACPA), Tenderness in Joints Count (TJC), Swelling in Joints Count (SJC), General Health Form (GHF), DAS28ESR, DAS28CRP and Disease duration of disease were significant among the group of patients. The gene discussed is PRTN3; the disease is rheumatoid arthritis.