SCN5A and Schnyder corneal dystrophy: On the other hand, early ICD implantation should be considered in patients with high-risk features as positive LGE with high-risk LGE distributions on CMR [5] or confirmed genetic mutation associated with higher risk of SCD as lamin A/C protein, PLN, SCN5A, RBM20, FLNC, and DSP [60–62].