To examine the effect of ILK on the apoptosis of ESCC cells, flow cytometry was used to detect the CDDP-induced apoptosis of TE-1 and KYSE150 cells in the oe-ILK and sh-ILK groups, as well as the oe-NC and sh-NC groups. This evidence concerns the gene ILK and esophageal squamous cell carcinoma.