AIF1 and Granuloma: Five of the lesions were(pyo)granulomatous, dominated by Iba1-positive epithelioid macrophages; 4 ofthese formed “atypical” (pyo)granulomas with varying degrees of encapsulatingfibrosis (cases 2, 9, 21, and 22), whereas case 16 showed “organized”(pyo)granulomas.