Azebrafish model of ocular mycobacteriosis identified peripheral blood monocytes indeveloping granulomas within the choroid-RPE complex in the face of a grossly intactblood-retinal barrier, whereas these cells were not identified in uninfected eyes,suggesting breach of the normal mechanisms that confer ocular immune privilege.85 Our findings suggest that monocyte-recruitment signaling pathways arepreserved in cases of ocular mycobacteriosis,17 with subsequent maturation of peripheral monocytes to Iba1-positive,calprotectin-negative epithelioid macrophages. Here, AIF1 is linked to Granuloma.