PRKAR1A and malignant tumor of parathyroid gland: Additionally, four patients with parathyroid cancer had VUSs: two APC variants (c.5378C>G [p.Ala1793Gly] and c.890C>T [p.Thr297Ile]), one WT1 variant (c.1139G>A [p.Arg380Gln]), and one PRKAR1A variant (c.567A>C [p.Glu189As]).