PLOD2 and cancer: Figure 8 showed the immunohistochemical staining results of 20 pairs of gastric cancer and corresponding adjacent tissues. In the gastric cancer group, PLOD2 was significantly overexpressed, while the expression in adjacent tissues was low. The median values of the two groups were 4 and 2 respectively. There was significant difference in staining score (p < 0.001, Figure 8E). Figures 8A,B were cancer tissues, and Figures 8C,D were adjacent tissues. The results of HPA database also showed that the expression of PLOD2 in STAD was higher than that normal gastric tissue (Figures 8F,G).