Further, we obtained the differences in PLOD2 from the TCGA database between cancer and para-cancer in individual tumor samples; and as shown in Figure 1C, PLOD2 was highly expressed in 11 (ESCA, GBM, HNSC, KIRC, KIRP, LGG, LIHC, LUAD, LUSC, STAD, UCEC) of 20 different tumors, lowly expressed in 4 tumors (COAD, KICH, PRAD, READ). The gene discussed is PLOD2; the disease is cancer.