These hallmarks were mostly correlated with programmed cell death signaling pathways, suggesting regulation of the cell cycle to promote apoptosis of cancer cells by changing the gene expressions such as knockdown of KIF11 (Liu et al., 2021) and SNRPG (Lan et al., 2020),which is conducive to cancer control for patients of C2 subtype. The gene discussed is SNRPG; the disease is cancer.